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Nature Medicine, Published online: 30 October 2024; doi:10.1038/s41591-024-03215-zSingle-nucleus and single-cell RNA sequencing plus spatial profiling with four methods of core biopsies from 60 patients with metastatic breast cancer reveal patient-specific gene expression programs of breast cancer m…

Nature Medicine, Published online: 30 October 2024; doi:10.1038/s41591-024-03308-9Techniques for single-cell and spatial expression profiling hold great promise for defining the complexity of metastatic microenvironments, but different methods give different representations. We profile 67 biopsies o…

Nature Medicine, Published online: 31 October 2024; doi:10.1038/d41591-024-00076-4The twentieth century saw unprecedented rises in life expectancy in high-income countries, but data suggest that this trend will not continue in the current century without radical interventions to slow biological agin…

Nature Medicine, Published online: 31 October 2024; doi:10.1038/d41591-024-00077-3In British South Asian women, a culturally adapted and community-informed cognitive behavioral therapy intervention led to higher early recovery rates than the usual treatment….

Nature Climate Change, Published online: 03 October 2024; doi:10.1038/s41558-024-02139-3The dominant paradigm holding that science is always objective needs to be challenged. When scientists’ opinions about climate change and their own fears are seen as irrelevant, it suggests that science is…

Nature Climate Change, Published online: 04 October 2024; doi:10.1038/s41558-024-02151-7Climate change and economic inequality are critical issues, and we still lack understanding of the interaction between them. Multi-model analysis shows how climate policies compatible with the goals of the Paris …